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3D ceramic printing helps vaccine production

#SIU_news 2020-05-27 00:00:00

Today, leading companies and research centers have directed maximum efforts to create a vaccine against COVID-19. The rapid spread of the coronavirus epidemic has shown the need for urgent development of medicines that can defeat and prevent the disease. In this case, it is important to comply with strict safety criteria for medicines.

Advanced developments to help doctors

Three-dimensional ceramic printing can speed up the vaccine manufacturing process and make drug production more affordable. The Nessie project, launched last year, involves the production of large series of complex vaccines at low cost and innovative materials, respectively. The project aims to increase the efficiency of vaccine production and is already contributing to the development of new methods for cleaning viruses, such as adenovirus. The use of 3D printing will reduce production costs to such an extent that the medicine will be available even for those countries that could not afford basic vaccines.

The NESSIE project was initiated by the independent Norwegian research organization SINTEFF and the Portuguese biopharmaceutical center IBET. Cerpotech has proposed advanced ceramic powders for the production of functional materials. The company synthesizes high-quality raw materials, adapted to the specific requirements of the final product. The joint work of organizations is aimed at increasing the effectiveness of the drug and increasing the profitability of production.

The 3D printing technique for ceramics is considered expensive, but within the framework of the manufacture of new vaccines, it is able to optimize the process. Using an updated design for the production of chromatographic columns allowed us to improve separation and reduce the cost of the product. Already managed to create the first chromatographic media that pass the testing stage for the purification of adenovirus, which is the optimal carrier for the "delivery" of vaccine antigens.

Strengths of Digital Ceramic 3D Printing Technology

The innovative Nessie project demonstrates that cutting-edge technology helps improve the healthcare system and gives a chance to defeat the disease.

3D printing has been used in medicine since the turn of the century. Initially, these were dental implants, and now scientists create details of the skeleton, parts of blood vessels, tissues and organs. In a pandemic, technology has already helped to quickly provide hospitals with the necessary medical supplies and replaceable components for ventilators.

The use of innovative resources - technical ceramics, composites or high-performance polymers - allows you to quickly establish a safe production of affordable vaccines. Ceramics is efficient in aggressive environments, has high dielectric properties, radiation resistant and biocompatible.

3D printing makes it possible to precisely control the dose of drugs with complex drug release profiles and prolonged exposure. Pharmacists are created the conditions for a thorough analysis of the disease in order to determine the optimal combination of medicinal elements. At any time, the formula can be adjusted depending on the effect obtained.

3D printing helps you quickly reproduce components and not be dependent on complex supply chains.

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